A liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of vancomycin in human serum and plasma.
2026-08-12, Clinical chemistry and laboratory medicine (10.1515/cclm-2026-0509) (online)Sandra Fleischer, Neeraj Singh, Friederike Bauland, Andrea Geistanger, Judith Taibon, and Elie Fux (?)
Vancomycin is a glycopeptide antibiotic used to treat severe Gram-positive infections; its narrow therapeutic window makes therapeutic drug monitoring (TDM) critical. We report the development of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) candidate reference measurement procedure (RMP) to quantify vancomycin in human plasma and serum.
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