The Effect of Transpulmonary Pressure-Guided Positive End-Expiratory Pressure Titration on Pulmonary Arterial Compliance in Acute Respiratory Distress Syndrome Patients: A Single-Center, Randomized Controlled Pilot Pathophysiological Study.

Tang, Xiao; Li, Ting; Yang, Hua; Liu, Ya-Lan; Lyu, Wen-Rui; Zhao, Yu; Li, Hai-Chao; Li, Meng; Li, Hu; Jin, Yu; Li, Xu-Yan; Tong, Zhao-Hui; Sun, Bing

doi:10.1097/CCE.0000000000001461

The Effect of Transpulmonary Pressure-Guided Positive End-Expiratory Pressure Titration on Pulmonary Arterial Compliance in Acute Respiratory Distress Syndrome Patients: A Single-Center, Randomized Controlled Pilot Pathophysiological Study.

2026-08-05, Critical Care Explorations (10.1097/CCE.0000000000001461) (online)
Xiao Tang, Ting Li, Hua Yang, Ya-Lan Liu, Wen-Rui Lyu, Yu Zhao, Hai-Chao Li, Meng Li, Hu Li, Yu Jin, Xu-Yan Li, Zhao-Hui Tong, and Bing Sun (?)

To compare the function of positive end-expiratory pressure (PEEP) titration guided by transpulmonary pressure (Ptp) with traditional lung-protective ventilation to optimize pulmonary arterial compliance (Cpa) in acute respiratory distress syndrome (ARDS) patients.

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The Effect of Transpulmonary Pressure-Guided Positive End-Expiratory Pressure Titration on Pulmonary Arterial Compliance in Acute Respiratory Distress Syndrome Patients: A Single-Center, Randomized Controlled Pilot Pathophysiological Study.